Canthaxanthin is a type of carotenoid pigment with an orange-red colour. It occurs naturally in many foods such as mushrooms, crustaceans, fish and eggs. Engineering Escherichia coli for Canthaxanthin. Astaxanthin and canthaxanthin are. was added to the β-carotene synthesis operon for canthaxanthin synthesis. The present invention relates to a novel process for preparing the carotenoids canthaxanthin (Ia) and astaxanthin (Ib) which are in demand. A synthesis designed for. Canthaxanthin can also cause diarrhea, nausea, stomach cramps, dry and itchy skin, hives, orange or red body secretions, and other side effects. Engineering Escherichia coli for canthaxanthin and astaxanthin biosynthesis. The carotenoid synthesis operons are assembled from genes isolated from carotenogenic. 2 The SCAN has delivered an opinion in December 1982 (fourth series) on the use of canthaxanthin in feedingstuffs for salmon and trout. The FAO/WHO Joint Expert. Synthesis of astaxanthin by Wittig reaction. Metabolic engineering. for example, the extraction of canthaxanthin (a precursor to astaxanthin). Synthesis of canthaxanthin 873 The isomerization of the epoxide 4 to the aldehyde 5 was not a trivial problem at first and while numeros Lewis acids didgive the. New approaches to the synthesis of canthaxanthin on ResearchGate, the professional network for scientists. A new synthesis of canthaxanthin via a Wittig coupling of the C 15 phosphonium salt 16 and the symmetrical dialdehyde 3 is reported. Several routes to the key.