Award Ceremony Speech. Stanley Prusiner suggested that the harmful prion. rendered strong support for the correctness of Prusiner's prion hypothesis. The controversial protein-only hypothesis of prion propagation. subsequently moved forward by Stanley Prusiner's group. Evidence supporting the prion hypothesis Stanley B. Prusiner - Biographical. My history is not atypical of many Americans: born in the midwest, educated in the East, and now living in the West. Stanley Prusiner discovered the prion, or proteinaceous infectious particle. Even now, not all researchers are wholly convinced by the prion hypothesis. Although this discovery puts a hole in the general prion hypothesis. for Neurodegenerative Diseases – labs studying prion diseases, run by Stanley B. Prusiner, MD; Prusiner's Prion Hypothesis. Prions were first hypothesized in 1982 by Stanley B. Prusiner of UCSF, who was awarded the Nobel Prize in physiology or medicine in 1997. Prion Diseases and the BSE Crisis Stanley B. Prusiner Prion hypothesis proven? In vitro. of proof for the prion hypothesis, Stanley Prusiner's Nobel-winning. patients who died of the prion disease called. In 1982 Stanley Prusiner introduced the term “Prion” to describe a new kind of infectious agent formed from proteins. His hypothesis that diseases such as scrapie. Stanley Benjamin Prusiner M.D (born May 28, 1942 [3]) is an American neurologist and biochemist. Currently [when?] the director of the Institute for Neurodegenerative.